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A method for the synthesis of 1,3-benzoxazine-4-ketone was developed using 2-hydroxybenzonitriles and ketones as raw materials with the promotion of ZnCl 2 .

ZnCl2-promoted domino reaction of 2-hydroxybenzonitriles with ketones for synthesis of 1,3-benzoxazin-4-ones

ZnCl₂-promoted domino reaction of 2-hydroxybenzonitriles with ketones for synthesis of 1,3-benzoxazin-4-ones