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A novel SERS immunoassay platform for simultaneous detection of SCCA and survivin based on Au–Ag nanoshells (Au–AgNSs) combined with a single-layer Au–AgNB array substrate was proposed in the current study.

rsc advances

A sandwich SERS immunoassay platform based on a single-layer Au–Ag nanobox array substrate for simultaneous detection of SCCA and survivin in serum of patients with cervical lesions