English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Hyperpolarization methods in magnetic resonance overcome sensitivitylimitations, especially for low-{\gamma} nuclei such as 13C and 15N. SignalAmplification By Reversible Exchange (SABRE) and extended SABRE (X-SABRE) areefficient and low-cost methods for generating large polarizations on a varietyof nuclei, but they most commonly use low magnetic fields ({\mu}T-mT). Highfield approaches, where hyperpolarization is generated directly in thespectrometer, are potentially much more convenient but have been limited toselectively hyperpolarize single targets. Here we introduce a new pulsesequence-based approach that affords broadband excitation of SABREhyperpolarization at high magnetic fields without having to tailor pulsesequence parameters to specific targets. This permits simultaneoushyperpolarization of multiple targets for the first time at high field andoffers a direct approach to integration of high-field SABRE hyperpolarizationinto routine NMR applications, such as NMR-based metabonomics and biomolecularNMR.

Phase coherent excitation of SABRE permits simultaneous hyperpolarization of multiple targets at high magnetic field