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We describe here a rapid and straightforward solvent-free method to access phenylthiazolo[5,4- b ]pyridines using a Nd-YAG laser NANO-NY81-10 ( λ  = 355 nm, 10 Hz pulse frequency; 8 ns pulse duration).

Laser synthesis: a solvent-free approach for the preparation of phenylthiazolo[5,4-b]pyridine derivatives