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Immobilised whole-cell ( R )-transaminases (TAs) enabled synthesis of either ( R )- or ( S )-enantiomers of drug-like amines from prochiral ketones or from racemic amines, respectively, in &gt;95% ee.

Transaminase-mediated synthesis of enantiopure drug-like 1-(3′,4′-disubstituted phenyl)propan-2-amines