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Moutan Cortex (MC) and Moutan Cortex charcoal (MCC) are two kinds of Chinese medicinal materials and effective substances are still unclear. A PK-PD model for MC/MCC is proposed using the support vector regression with particle swarm optimization.

rsc advances

Pharmacokinetic–pharmacodynamic modeling for Moutan Cortex/Moutan Cortex charcoal and the contributions of the chemical component using support vector regression with particle swarm optimization