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250 years after his death, Thomas Chatterton continues to enchant and create discussion. Did he commit suicide, or did he accidentally overdose on Laudanum? UPLC-MS/MS is used to try to solve the mystery of his untimely death.

An LC-MS/MS analysis of opiate residues on Thomas Chatterton's (1752–1770) memorandum book – Did he die from a laudanum overdose?