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Diketopyrrolopyrrole-based fluorescent probes have been developed for the detection of low pH and Zn 2+  in an AND logic fashion. They can discriminate between cancerous and healthy prostate tissue.

Diketopyrrolopyrrole-based fluorescence probes for the imaging of lysosomal Zn2+ and identification of prostate cancer in human tissue

Diketopyrrolopyrrole-based fluorescence probes for the imaging of lysosomal Zn²⁺ and identification of prostate cancer in human tissue