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A pyrazolopyrimidine-based fluorescent sensor  L  was developed and applied for detection of Cu 2+  and Ni 2+  in ethanol solution by photoluminescence quenching. It shows low cytotoxicity and good imaging characteristics for Cu 2+  and Ni 2+  in living cells.

rsc advances

Dual-response detection of Ni<sup>2+</sup> and Cu<sup>2+</sup> ions by a pyrazolopyrimidine-based fluorescent sensor and the application of this sensor in bioimaging

Dual-response detection of Ni2+ and Cu2+ ions by a pyrazolopyrimidine-based fluorescent sensor and the application of this sensor in bioimaging

Dual-response detection of Ni²⁺ and Cu²⁺ ions by a pyrazolopyrimidine-based fluorescent sensor and the application of this sensor in bioimaging