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A AuNPs–AgNWs decorated silicon wafer was used as a non-destructive and label-free tool in SERS spectroscopy to detect and distinguish the cellular composition of CYP2C9-expressing cells (293T-Mig-2C9) and non-expressing cells (293T-Mig-R1).

rsc advances

The label-free detection and distinction of CYP2C9-expressing and non-expressing cells by surface-enhanced Raman scattering substrates based on bimetallic AuNPs–AgNWs