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Based on surface-enhanced Raman scattering (SERS) technology, Au@Ag@4MBA@5′-NH 2 -ssDNA probes and a Ag/TiO 2 @3′-NH 2 -ssDNA substrate were prepared and constructed into a sandwich structure to develop a high sensitivity bioassay of miRNA-21.

SERS-based sandwich bioassay protocol of miRNA-21 using Au@Ag core–shell nanoparticles and a Ag/TiO2 nanowires substrate

SERS-based sandwich bioassay protocol of miRNA-21 using Au@Ag core–shell nanoparticles and a Ag/TiO₂ nanowires substrate