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The glucuronidation pathways of shogaols ([6]-shogaol, [8]-shogaol and [10]-shogaol) were characterized in human tissues and recombinant human UDP-glucosyltransferases, and UGT2B7 was identified as the main contributor to their glucuronidation.

rsc advances

Glucuronidation of [6]-shogaol, [8]-shogaol and [10]-shogaol by human tissues and expressed UGT enzymes: identification of UGT2B7 as the major contributor