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Applanatumines B–D ( 1–3 ), three pairs of dimeric meroterpenoid enantiomers featuring the presence of a 6-oxo-4,4a,5,5a,6,8,8a,8b-octahydrofuro[3′,4′:4,5]cyclopenta[1,2- b ]pyran-3-carbaldehyde structure core, were isolated from the fruiting bodies of  Ganoderma applanatum .

(±)-Applanatumines B–D: novel dimeric meroterpenoids from Ganoderma applanatum as inhibitors of JAK3