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The efficient asymmetric Michael addition reactions of pyrrolones with chalcones catalyzed by a simple and commercially available chiral 1,2-diaminocyclohexane-2-(N-Boc-amino)benzoic acid have been developed to provide the corresponding Michael adducts in good yields (up to 90%) and high enantioselectivities (up to 95% ee).

Asymmetric Michael addition reactions of pyrrolones with chalcones catalyzed by vicinal primary-diamine salts