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An operationally simple, one-pot, two-step tandem procedure that allows the incorporation of radioactive iodine into aryl amines via stable diazonium salts is described. The mild conditions are tolerant of various functional groups and substitution patterns, allowing late-stage, rapid access to a wide range of 125 I-labelled aryl compounds and SPECT radiotracers.

A one-pot radioiodination of aryl amines via stable diazonium salts: preparation of 125I-imaging agents

A one-pot radioiodination of aryl amines via stable diazonium salts: preparation of ¹²⁵I-imaging agents