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A  series  of  new  thermo-gelling  polymers  based  on  thermo-responsive  poly(2-alkyl-2-oxazoline)s  has  been  prepared  by  grafting  different poly(2-alkyl-2-oxazolines)  onto  a  polar carboxymethylcellulose backbone. Thermo-reversible gelation is observed at low concentrations (less than 5% by weight of thermo-gelling polymer).Rheology reveals that these polymers show tuneable  gelation  temperatures,  which  vary  with  con centration  and  poly(2-oxazoline) composition. This allows the gelation point to be adjusted to biologically relevant temperatures, offering a novel material with potential applications in areas such as drug delivery and tissue engineering

Synthesis and gelation properties of poly(2-alkyl-2-oxazoline) based thermo-gels