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We have synthesized a bifunctional erbium-porphyrin tumor imaging and PDT agent (Er-R3) that is capable of killing bladder cancer cells via its selective binding to the integrin α v β 3 isoform overexpressed on the cell membrane.

αvβ3-Isoform specific erbium complexes highly specific for bladder cancer imaging and photodynamic therapy

α_vβ₃-Isoform specific erbium complexes highly specific for bladder cancer imaging and photodynamic therapy