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The unsaturated disaccharide isomers of chondroitin sulfate (CS) obtained by enzymatic digestion of the polysaccharide can be differentiated in mixtures by ion mobility MS (A) as well as pulsed-field gradient NMR (B).

analytical methods

Comparison of ion mobility-mass spectrometry and pulsed-field gradient nuclear magnetic resonance spectroscopy for the differentiation of chondroitin sulfate isomers