English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

We present a simple route to circumvent kinetic traps which affect many typesof DNA nanostructures in their self-assembly process. Using this method, a new2D DNA lattice made up of short, single-stranded tile (SST) motifs was created.Previously, the growth of SST DNA assemblies was restricted to 1D (tubes andribbons) or finite-sized 2D (molecular canvases). By utilizing thesubstrate-assisted growth method, sets of SSTs were designed as unit cells toself-assemble into periodic and aperiodic 2D lattices which continuously growboth along and orthogonal to the helical axis. Notably, large-scale ($\sim 1$$\mu$m$^2$) fully periodic 2D lattices were fabricated using a minimum of just2 strand species. Furthermore, the ability to create 2D lattices from a fewmotifs enables certain rules to be encoded into these SSTs to carry outalgorithmic self-assembly. A set of these motifs were designed to executesimple 1-input 1-output COPY and NOT algorithms, the space-time manifestationswhich were aperiodic 2D algorithmic SST lattices. The methodology presentedhere can be straightforwardly applied to other motifs which fall into this typeof kinetic trap to create novel DNA crystals.

Substrate-assisted 2D DNA lattices and algorithmic lattices from single-stranded tiles