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N-(2-Acetamido)-2-aminoethanesulfonic acid (ACES), one of Good's buffers, was applied to pH imaging using hyperpolarized (13)C magnetic resonance spectroscopy. Rapid NMR- and MRI-based pH measurements were obtained by exploiting the sensitive pH-dependence of its (13)C chemical shift within the physiologic range.

Application of Good's buffers to pH imaging using hyperpolarized13C MRI

Application of Good's buffers to pH imaging using hyperpolarized¹³C MRI