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We investigate binary mixtures of large colloids interacting through softpotentials with small, ideal depletants. We show that softness has a dramaticeffect on the resulting colloid-colloid effective potential when thedepletant-to-colloid size ratio $q$ is small, with significant consequences onthe colloidal phase behaviour. We also provide an exact relation that allows usto obtain the effective pair potential for {\it any} type of colloid-depletantinteractions in the case of ideal depletants, without having to rely oncomplicated and expensive full-mixture simulations. We also show that softrepulsion among depletants further enhances the tendency of colloids toaggregate. Our theoretical and numerical results demonstrate that --- in thelimit of small $q$ --- soft mixtures cannot be mapped onto hard systems andhence soft depletion is not a mere extension of the widely used Asakura-Oosawapotential.

How soft repulsion enhances the depletion mechanism