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We have developed a (68)Ga metal chelating bioorthogonal tetrazine dextran probe that is highly reactive with trans-cyclooctene modified monoclonal antibodies for multistep imaging applications. Confocal microscopy and positron emission tomography (PET) were used to characterize the dextran probe in vitro and in vivo.

68Ga chelating bioorthogonal tetrazine polymers for the multistep labeling of cancer biomarkers

⁶⁸Ga chelating bioorthogonal tetrazine polymers for the multistep labeling of cancer biomarkers