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Unraveling pyramidal cell structure is crucial to understanding cortical circuit computations. Although it is\udwell known that pyramidal cell branching structure differs in the various cortical areas, the principles that\uddetermine the geometric shapes of these cells are not fully understood. Here we analyzed and modeled with a\udvon Mises distribution the branching angles in 3D reconstructed basal dendritic arbors of hundreds of\udintracellularly injected cortical pyramidal cells in seven different cortical regions of the frontal, parietal, and\udoccipital cortex of the mouse. We found that, despite the differences in the structure of the pyramidal cells in\udthese distinct functional and cytoarchitectonic cortical areas, there are common design principles that\udgovern the geometry of dendritic branching angles of pyramidal cells in all cortical areas

Branching angles of pyramidal cell dendrites follow common geometrical design principles in different cortical areas