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Design A 3-year randomised controlled trial in 180 13 to 14-year-old subjects.Intervention Either 0.1% fluoride or 1% chlorhexidine/thymol varnish professionally applied after prophylaxis every 3 months.Outcome measure Caries increment was identified using bitewing radiographs. The assessor was blind to treatment allocation.Results There were no significant differences between the two groups, with about three new approximal surfaces per child decayed or filled in each group, mostly restricted to the enamel surface (see Table 1).Conclusions There was no difference in caries experience with the use of fluoride varnish compared with the use of chlorhexidine varnish.

No difference between topical chlorhexidine and fluoride varnishes in preventing caries?