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Hangzhou Bay is facing severe anthropogenic perturbation because of its geographic position. We studied species-specific bioaccumulation of metals in commercially important fishes and shellfishes, and calculated the potential human health hazards through their consumption, which has not been reported earlier from this area. The hierarchy of metal concentration in organisms was in the decreasing order of Zn (10.32 ± 7.13) &gt; Cu (2.40 ± 2.66) &gt; As (0.42 ± 0.26) &gt; Cr (0.11 ± 0.08) &gt; Cd (0.07 ± 0.07) &gt; Pb (0.05 ± 0.02) &gt; Hg (0.012 ± 0.009). Except for Cd and As concentrations in fishes, metal concentrations have not exceeded the national and international guideline values.  P. laevis  and  P. trituberculatus  were the most bioaccumulative of the species studied. According to the non-carcinogenic risk assessment, children were more susceptible to metal contamination than adults. The carcinogenic risk (CR) values indicated that children were likely to experience carcinogenic threats for taking cancer-causing agents As and Cd through fish consumption. In terms of organisms, intake of two crab species,  P. trituberculatus  and  E. sinensis , as well as the oyster species  P. laevis , could be detrimental to consumers.

Bioaccumulation and potential human health risks of metals in commercially important fishes and shellfishes from Hangzhou Bay, China