English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Adequate water supply is one of the public health issues among the population living in low-income settings. Vibriosis remain a significant health challenge drawing the attention of both healthcare planners and researchers in South West districts of Uganda. Intending to clamp down the disease cases in the safest water deprive locality, we investigated the virulent toxins as contaminants and epidemiologic potentials of  Vibrio  species recovered from surface waters in greater Bushenyi districts, Uganda. Surface water sources within 46 villages located in the study districts were obtained between June and October 2018. Standard microbiological and molecular methods were used to analyse samples. Our results showed that 981 presumptive isolates retrieved cell counts of 10–100 CFU/g, with, with (640) 65% confirmed as  Vibrio  genus using polymerase chain reaction, which is distributed as follows;  V. vulnificus  46/640 (7.2%),  V. fluvialis  30/594 (5.1),  V. parahaemolyticus  21/564 (3.7),  V. cholera  5/543 (0.9),  V. alginolyticus  62/538 (11.5) and  V. mimicus  20/476 (4.2). The virulence toxins observed were heat-stable enterotoxin ( stn ) 46 (82.10%),  V. vulnificus  virulence gene ( vcgCPI ) 40 (87.00%), extracellular haemolysin gene { vfh  21 (70.00)} and Heme utilization protein gene { hupO  5 (16.70)}. The cluster analysis depicts  hupO  (4.46% n = 112);  vfh  (18.75%, n = 112);  vcgCPI  and  stn  (35.71%, & 41.07%, n = 112). The principal component analysis revealed the toxins ( hupO, vfh ) were correlated with the isolate recovered from Bohole water (BW) source, while ( vcgCPI, stn ) toxins are correlated with natural raw water (NRW) and open springs (OS) water sources isolates. Such observation indicates that surface waters sources are highly contaminated with an odds ratio of 1.00, 95% CI (70.48–90.5), attributed risk of (aR = 64.29) and relative risk of (RR = 73.91). In addition, it also implies that the surface waters sources have > 1 risk of contamination with  vfh  and > six times of contamination with  hupO  (aR = 40, − 66). This is a call of utmost importance to the population, which depends on these water sources to undertake appropriate sanitation, personal hygienic practices and potential measures that ensure water quality.

Epidemiologic potentials and correlational analysis of Vibrio species and virulence toxins from water sources in greater Bushenyi districts, Uganda