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Magnetic hyperthermia is one of the most promising techniques for treating gynecological cancer, where magnetite (Fe 3 O 4 ) is the most common nanomaterial used as a magnetic hyperthermia agent. Here, we demonstrate that optimal Fe 3 O 4  nanorods (NRs) can act as a magnetic hyperthermia agent with higher specific absorption rate (SAR), which is mostly attributed to their enhanced surface anisotropy. As a result, Fe 3 O 4  NRs could effectively hinder the growth of gynecological cancer cells in nude mice models, again demonstrating its good magnetic heating properties. These results provide a powerful basis for the development of an ideal magnetic hyperthermia agent with enhanced SAR, thereby effectively treating gynecological cancer in clinical practice.

Tunable Fe3O4 Nanorods for Enhanced Magnetic Hyperthermia Performance