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This study evaluates the prevalence, diversity, and genetic profiles of  Candida albicans  isolates recovered from the oral cavities of haemodialysis patients. Oral swab samples were obtained from haemodialysis patients (n = 126) and healthy control subjects (n = 233) and  Candida  species were characterised. There was no significant difference between the haemodialysis and control groups in the prevalence of yeast carriers (23.6%  vs . 31.0%, respectively) or  C. albicans  carriers (19.8%  vs . 21.0%, respectively).  C. albicans  was the most populous species in both cohorts, followed by  C. parapsilosis .  C. parapsilosis  and  C. glabrata  were more prevalent in the haemodialysis group than in the control group ( C. parapsilosis  5.6%  vs . 0.9% and  C. glabrata  3.2%  vs . 0.4%, respectively;  P  < 0.05).  C. albicans  isolates were analysed by multilocus sequence typing and the results were used to construct a phylogenetic tree. Most haemodialysis isolates were placed into Clade 4 (20.0%) and Clade 19 (16.0%) and most control isolates into Clade 8 (17%) and Clade 4 (14.9%). Differences in the strain abundance in each clade were not statistically significant between the two groups. Moreover, there was no significant association between the health status or diagnosis and either the sequence types or clades.

Multilocus sequence typing of Candida albicans isolates from the oral cavities of patients undergoing haemodialysis