English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

We previously identified novel bioactive polysaccharides from  Bactrocera cucurbitae  and  Antheraea yamamai  that activate innate immunity in RAW264 murine macrophages. However, in terms of potential applications in the cultivation of prawns, there were problems with the availability of these insects. However, we have now identified a polysaccharide from  Bombyx mori  that activates innate immunity in RAW264 cells and penaeid prawns. This purified polysaccharide, termed silkrose of  B. mori  (silkrose-BM), has a molecular weight of 1,150,000 and produces a single symmetrical peak on HPLC. Eight of nine constitutive monosaccharides of silkrose-BM are concomitant with dipterose of  B. cucurbitae  (dipterose-BC) and silkrose of  A. yamamai  (silkrose-AY). The major differences are found in the molar ratios of the monosaccharides. Silkrose-BM is approximately 500-fold less potent than silkrose-AY (EC 50 : 2.5 and 0.0043 μg/mL, respectively) in a nitrite oxide (NO) production assay using RAW264 cells. However, the maximum NO production for silkrose-BM and AY were comparable and higher than that of the lipopolysaccharide of  Escherichia coli . The survival of penaeid prawns ( Litopenaeus vannamei  and  Marsupenaeus japonicus ) after infection with  Vibrio penaecida  was significantly improved by both dietary silkrose-BM and  B. mori  pupae. This suggests that silkrose-BM effectively prevents vibriosis in penaeid prawns via the activation of innate immunity.

The silkrose of Bombyx mori effectively prevents vibriosis in penaeid prawns via the activation of innate immunity