English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Conventional cytopathology examination of respiratory samples can aid in identifying  Aspergillus  but with poor sensitivity, so this study aimed to assess the potential of the liquid-based cytopathology test (LCT) for improving the identification of  Aspergillus  in respiratory samples following Papanicolaou’s or Special staining with Grocott’s methenamine silver or periodic acid-Schiff staining. Paired bronchial brushing samples (n = 54) and sputum samples (n = 117) from 171 patients with pulmonary aspergillosis were prepared as slides using either conventional cytopathology or SurePath LCT. LCT slides were generally superior to conventional slides, showing smaller cell monolayer surface area, clearer background and more distinct stereoscopic cytological features. For Papanicolaou’s staining, LCT-prepared slides allowed a higher positive rate of  Aspergillus  identification than conventional slides for bronchial brushing samples (59.25% vs. 20.37%,  P  < 0.05) and sputum samples (29.05% vs. 8.55%,  P  < 0.05). Similarly, Special staining of LCT-prepared slides showed a higher positive rate of  Aspergillus  identification for bronchial brushing samples (83.33% vs. 57.41%,  P  < 0.05) and sputum samples (43.59% vs. 19.66%,  P  < 0.05). This preliminary study suggests that LCT may be better than conventional slide preparation for identifying  Aspergillus  in respiratory samples from patients with pulmonary aspergillosis.

Liquid-based cytopathology test as a novel method to identify Aspergillus in patients with pulmonary aspergillosis