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Minimally invasive medical procedures, such as endovascular catheterization,have drastically reduced procedure time and associated complications. However,many regions inside the body, such as in the brain vasculature, still remaininaccessible due to the lack of appropriate guidance technologies. Here,experimentally and through numerical simulations, we show that tetheredultra-flexible endovascular microscopic probes can be transported throughtortuous vascular networks almost effortlessly by harnessing hydrokineticenergy. Dynamic steering at bifurcations is performed by deformation of theprobe head using magnetic actuation. We developed an endovascular microrobotictoolkit with a cross-sectional area that is approximately three orders ofmagnitude smaller than the smallest microcatheter currently available. Ourtechnology has the potential to revolutionize the state-of-the-art practices asit enhances the reachability, reduces the risk of iatrogenic damage,significantly increases the speed of robot-assisted interventions, and enablesthe deployment of multiple leads simultaneously through a standard needleinjection.

Flow-driven robotic navigation of microengineered endovascular probes