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The T cell cytokine profile is a key prognostic indicator of post-surgical outcome for colorectal cancer (CRC). Whilst T H 1 (IFN-γ + ) cell-mediated responses generated in CRC are well documented and are associated with improved survival, antigen-specific T H 17 (IL-17A + ) responses have not been similarly measured.

Prognostic significance of interleukin-17A-producing colorectal tumour antigen-specific T cells