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This pooled analysis investigated the prognostic value of depth of response in two cohorts of patients with BRAF V600 -mutated metastatic melanoma treated with vemurafenib or cobimetinib plus vemurafenib.

Impact of depth of response on survival in patients treated with cobimetinib ± vemurafenib: pooled analysis of BRIM-2, BRIM-3, BRIM-7 and coBRIM