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Previous studies have reported up to 50% of ductal carcinoma in situ (DCIS), is HER2 positive, but the frequency of HER2-positive invasive breast cancer (IBC) is lower. The aim of this study is to characterise HER2 status in DCIS and assess its prognostic value.

The clinical and biological significance of HER2 over-expression in breast ductal carcinoma in situ: a large study from a single institution