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microRNAs (miRNAs) are involved in a wide variety of biological processes and play roles in the regulation of Toll-like receptor (TLR) signals. We hypothesized that lipopolysaccharide (LPS)-induced miRNAs in the leukocytes from cord blood (CB) play an important role in newborn innate immunity, specifically in the regulation of the TLR signaling pathway.

In vitro screening of LPS-induced miRNAs in leukocytes derived from cord blood and their possible roles in regulating TLR signals