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Background: In neonatal RDS bolus administration of surfactant (SF) is an effective therapy, however has been linked to “peridosing adverse events”. Aerosolization of SF has emerged as feasible alternative to instillation for RDS.

pediatric research

Acute and Sustained Effects of Aerosolized vs. Bolus Administration Surfactant on Pulmonary Mechanics and Systemic and Cerebral Haemodinamic in Premature Lambs with Respiratory Distress Syndrome