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Background and aims: Epidemiological studies clearly link intrauterine growth restriction (IUGR) with increased risk of heart disease in adulthood; mechanisms leading to this increased risk are poorly understood. The aim of this study was to examine the biochemical composition of the left ventricular (LV) myocardium in adulthood in growth-restricted and non-growth-restricted rat offspring.

pediatric research

Evidence of Altered Biochemical Composition in the Myocardium of Adult Intrauterine Growth Restricted Offspring using FTIR Micro-Spectroscopy: Implications for the Programming of Heart Disease