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Objective:  This study examined the efficacy of a commercially available, portion-controlled diet (PCD) on body weight and HbA 1c  over 6 months in obese patients with type 2 diabetes.    Research Design and Methods:  One-hundred participants with a mean±s.d. age of 55.6±10.6 year, body weight of 102.9±18.4 kg and HbA 1c  of 7.7±1.3% were randomly assigned to a 9-session group lifestyle intervention that included a PCD or to a 9-session group program of diabetes self-management education (DSME). Participants in the two groups were prescribed the same goals for energy intake (1250–1550 kcal per day) and physical activity (200 min per week).    Results:  While both groups produced significant improvements in weight and HbA 1c  after 6 months of treatment, PCD participants lost 7.3 kg [95% confidence interval (CI): −5.8 to −8.8 kg], compared with 2.2 kg (95% CI: −0.7 to −3.7 kg) in the DSME group ( P <0.0001). Significantly more PCD than DSME participants lost ⩾5% of initial weight (54.0% vs 14.0%,  P <0.0001) and ⩾10% (26.0% vs 6.0%,  P <0.0001). HbA 1c  declined by 0.7% (95% CI: −0.4 to −1.0%) in the PCD group, compared with 0.4% (95% CI: −0.1 to −0.7%) in DSME ( P <0.026). Across both groups, larger weight losses were associated with greater reductions in HbA 1c  ( r =0.52,  P <0.0001).    Conclusions:  These findings demonstrate that a commercially available portion-controlled meal plan can induce clinically meaningful improvements in weight and glycemic control in obese individuals with type 2 diabetes. These data have implications for the management of obesity in primary care, as now provided by the Centers for Medicare and Medicaid Services.

A randomized comparison of a commercially available portion-controlled weight-loss intervention with a diabetes self-management education program