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<p>The envelope glycoprotein spike, the sole antigen on the Lassa virus (LASV) surface, constitutes the focal point ofthe host neutralizing immune response. A high-resolution structure of the trimeric LASV glycoprotein in an antibodyboundform illuminates the molecular architecture of the antigen and reveals the mode of action of the mostabundant known class of Lassa-specific human neutralizing antibodies.</p

Human antibody pieces together the puzzle of the trimeric Lassa virus surface antigen