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Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan*Corresponding author, Email: oekenji@fujita-hu.ac.jpIn addition to its characteristics as a DNA binding transcription factor, HMGA1a is known to bind RNA, sequence specifically and regulate aberrant splicing of the Presenilin-2 gene in sporadic Alzheimer’s disease

An RNA cis-element upstream of the HMGA1a binding site affects exon exclusion caused by HMGA1a