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Molecular biology data are subject to terms of use that vary widely betweendatabases and curating institutions. This research presents a taxonomy ofcontractual and technical restrictions applicable to databases in life science.It builds upon research led by Science Commons demonstrating why open data andthe freedom to integrate facilitate innovation and how this openness can beachieved. The taxonomy describes technical and legal restrictions applicable tolife science databases, and its metadata have been used to assess terms of useof databases hosted by Life Science Resource Name (LSRN) Schema. While a fewpublic domain policies are standardized, most terms of use are not harmonized,difficult to understand and impose controls that prevent others fromeffectively reusing data. Identifying a small number of restrictions allows oneto quickly appreciate which databases are open. A checklist for data opennessis proposed in order to assist database curators who wish to make their datamore open to make sure they do so.

Check Your Data Freedom: A Taxonomy to Assess Life Science Database Openness