English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Robert W McCarley, MD, known to all as ‘Bob,’ died on 27 May 2017. His death was unexpected, and followed a meeting the day before with members of the executive committee of psychiatry, and his weekly Friday meetings with basic neuroscientists in his lab. On Saturday he was driving to his summer home in Westport, MA, with his wife Alice to prepare for a birthday for June, one of their seven grandchildren. He felt ill on arrival and was taken to the hospital, where he died later that day from a heart attack. Bob was born on 17 August 1937 in Mayfield, KY, and came to Harvard College in 1955 on a full scholarship at the age of 18. Except for one year, he never left. He graduated Summa cum laude and was elected to the Alpha Chapter of Phi Beta Kappa. He then spent one year as a Fulbright Scholar in Psychology at Johannes Gutenberg Universitaet, Mainz, Germany. He was also a National Scholar at both Harvard College and Harvard Medical School. He interned at Brigham and Women’s Hospital. It was here that he met Alice Bowen, whom he married in 1968. They began their life together first in Brighton and then moved to their Newton home, where they remained and raised their two sons, Robert and Scott. Bob began his research career while still a resident in psychiatry at Massachusetts Mental Health Center. He worked closely with Dr J Allan Hobson. In 1977 he and Allan published an important paper on the activation-synthesis theory of dreams, which posits that dreams do not have meanings but are the result of the brain’s attempt to make sense of the random firing of neurons. Bob’s research interests were also in studying the brainstem and mechanisms in the brainstem that control REM sleep. He published Brain Control of Wakefulness and Sleep with Dr Mircea M Steriade in 2005. In the previous year, 2004, he published an important paper on adenosine and sleep wakefulness regulation with Drs Radhika Basheer, Robert Strecker, and Mahesh Thakkar. In 1985 Bob moved from Massachusetts Mental Health Center to the Veterans Affairs Boston Healthcare System (VABHS) in Brockton, MA. He was Professor and Chair of the Harvard Medical School Department of Psychiatry at VABHS, founding Director of the Laboratory of Neuroscience, and Director and later Associate Director of the Mental Health Service. The Laboratory of Neuroscience has two divisions, a basic neuroscience and a clinical neuroscience division, following his two passions, sleep and mechanisms underlying sleep, and schizophrenia and related psychosis. As a clinically trained and board-certified psychiatrist, he was interested in neuroscience related to schizophrenia, particularly as new technologies made it possible to examine brain physiology and structure in psychiatric populations. This work began in the 1980s with neurophysiology studies of the brain using a form of EEG known as event-related potentials, and with emerging magnetic resonance imaging (MRI) technology to investigate structural abnormalities in patients with schizophrenia. This newer technology, which included the quantitative processing of MR images, was adapted from satellite technology. In 1992 he published a classic paper with Dr Martha Shenton, where they described an important relationship between volume reduction in a brain region involved in thought and language, the left superior temporal gyrus, and a measure of formal thought disorder that reflected disorganized thinking in patients with schizophrenia. The basic neuroscience division will continue with Drs Robert Strecker, Ritchie Brown, and Radhika Basheer at the helm, focusing on brain control of sleep and wakefulness, while the clinical neuroscience division will continue with Drs Margaret Niznikiewicz and Kevin Spencer at the helm, focusing on schizophrenia and related psychoses, using neurophysiological and neuroimaging techniques. Bob published 4450 peer-reviewed papers and received consistent funding from the NIH and the VA for both sleep research and for schizophrenia research. He served as President of the US Sleep Research Society and received top research prizes from the US Sleep Research Society, the American Academy of Sleep Medicine, and the American Psychiatric Association, and, in 1998, he received the Neuropsychopharmacology (2017) 42, 2468–2469 © 2017 American College of Neuropsychopharmacology. All rights reserved 0893-133X/17

Robert W McCarley—Pre-eminent Researcher, Mentor, and Friend