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Traditionally, luminescence has not been able to provide sufficient spatial resolution at the microscopic level without the use of expensive imaging equipment. The new Olympus LV200 microscope has changed all this; its unique optical geometry and precise incubation capabilities enable acquisition of even the faintest signals with cellular-level detail. This has opened up new frontiers in many areas of research, especially in the study of circadian rhythm–related events.

Bioluminescence microscopy for cellular level circadian analysis in the suprachiasmatic nucleus