English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

The evolutionary origins of lingulid brachiopods and their calcium phosphate shells have been obscure. Here we decode the 425-Mb genome of  Lingula anatina  to gain insights into brachiopod evolution. Comprehensive phylogenomic analyses place  Lingula  close to molluscs, but distant from annelids. The  Lingula  gene number has increased to ∼34,000 by extensive expansion of gene families. Although  Lingula  and vertebrates have superficially similar hard tissue components, our genomic, transcriptomic and proteomic analyses show that  Lingula  lacks genes involved in bone formation, indicating an independent origin of their phosphate biominerals. Several genes involved in  Lingula  shell formation are shared by molluscs. However,  Lingula  has independently undergone domain combinations to produce shell matrix collagens with EGF domains and carries lineage-specific shell matrix proteins. Gene family expansion, domain shuffling and co-option of genes appear to be the genomic background of  Lingula 's unique biomineralization. This  Lingula  genome provides resources for further studies of lophotrochozoan evolution.

The Lingula genome provides insights into brachiopod evolution and the origin of phosphate biomineralization