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Cardiovascular morbidity and mortality are elevated in patients with chronic kidney disease (CKD).1 Most of the studies evaluating the correlations between chronic renal dysfunction and cardiovascular disease (CVD) have been performed in patients with end-stage renal failure, whereas few data are available regarding cardiovascular abnormalities in patients with early-stage renal disease

Preclinical cardiovascular abnormalities in patients in early stages of renal disease without nephrotic syndrome