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The occurrence of organ-specific antigens on the surface of cells freshly isolated from normal adult rat liver and from liver cell lines cultured as monolayers for up to 6 months is demonstrated. Enzyme treatment used to disaggregate parenchymal cells from liver tissue did not result in appreciable changes in the antigen profile of the cell surface membrane.

Cultures from Adult Rat Liver Cells. II. Demonstration of Organ-Specific Cell Surface Antigens on Cultured Cells from Normal Liver