English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

THE study of intermediary metabolism in cultured mammalian cells has been greatly facilitated by the development of chromatographic methods of separation in conjunction with the availability of radioactively labelled substrates. Thus considerable information about the metabolism and biosynthetic capacities of long established cell cultures, such as HeLa cells, has been obtained in recent years (Eagle, 1959 ; Levintow and Eagle, 1961). This paper is concerned with a comparison of some aspects of intermediary metabolism of HeLa cells and a more recently instituted cell culture, human foetal liver cells (Westwood, MacPherson and Titmuss, 1957). The incorporation of radiocarbon from [14C]glucose, [2-14C]acetate and [1: 4-14C2]succinate into the soluble metabolic intermediates of both cell types was investigated. Although the qualitative patterns of incorporation of radioactivity were similar it was found that there were some important (liffereinces in the quantitative distribution of the isotope amongst the metabolic intermediates.

Intermediary Metabolism in HeLa and Human Foetal Liver Cells