English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

SKiN painting of female mice of the IF strain and its Fl hybrids with an oily solution of 9: 10-dimethyl-I :2-benzanthracene, now renamed 7, 12-dimethylbenz(a)anthracene, induced breast tumours and granulosa-celled tumours of the ovary in a high proportion of animals (Howell, Marchant and Orr, 1954). In a subsequent experiment (Marchant, 1959a, 1960) ovarian tumours arose in 14 out of 18 normal mice whose own ovaries were removed and replaced witl'l those of mice which had been pretreated with the carcinogen over a period of 90 days. Large cysts filled with clear fluid were also found in 7 of these animals. Another experiment (Marchant, 1959b) had shown significant changes in ovaries examined after 90 days of pretreatment with the carcinogen. They were atrophied, with almost complete destruction of follicles and diffuse luteinisation, and early tumour nodules had just begun to make their appearance. The present experiments were designed to discover whether ovaries grafted in much earlier stages of pretreatment with the carcinogen would develop ovariai-i tumours and cysts, and to see whether the grafting operation itself was effective in giving rise to tumours or cysts.

The Development of Ovarian Tumours in Ovaries Grafted from Mice Pretreated with Dimethylbenzanthracene