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ELSEWHERE (Galluzzi and Payne, 1955) we have dealt in detail with the sources and composition of 741 necropsies which form the basis of the present article. The more general aspects of blood-borne spread were also considered in the earlier work. Our purpose here is to consider specifically brain metastases arising from bronchial carcinoma. The reason for dealing separately with this topic is that it has been a matter of special interest for a number of years and might add useful facts to the current discussions on the proportion of deaths certified as lung cancer which is due to a real increase in the disease. Many authors in the past have remarked on the prevalence of this mode of spread and some, for example Willis (1953) and Bailey (1948) have discussed its natural history and pathology in some detail.

Brain Metastases from Primary Bronchial Carcinoma: A Statistical Study of 741 Necropsies