Differential Effects of Reduced Cyclic Stretch and Perturbed Shear Stress Within the Arterial Wall and on Smooth Muscle Function
Author(s) -
Tyler Thacher,
Rafaela da Silva,
Nikolaos Stergiopulos
Publication year - 2009
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1038/ajh.2009.193
Subject(s) - medicine , shear stress , vascular smooth muscle , anatomy , superoxide , fibronectin , biophysics , microbiology and biotechnology , chemistry , smooth muscle , materials science , biology , biochemistry , extracellular matrix , composite material , enzyme
Cyclic circumferential stretch and shear stress act in concert and yet are capable of independently mediating arterial smooth muscle function, modulating the production of superoxide and stimulating arterial remodeling.
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